Endocrine Abstracts

Background: The pregnancy-specific condition pre-eclampsia (PE) affects ~2% of women contributing to neonatal and maternal morbidity and has been linked with a deficiency in selenium. The iodothyronine deiodinases all contain selenium and play crucial roles in determining the circulating and intracellular levels of the active thyroid hormone. It is hypothesised that due to the role of deiodinases in extrathyroidal production of T3, thyroid-stimulating hormone (TSH) will be inc...